Cry-Baby is a 1990 American teen musical romantic comedy film written and directed by John Waters. It was the only film of Waters's over which studios were in a bidding war, coming off the heels of the successful Hairspray. The film stars Johnny Depp as 1950s teen rebel "Cry-Baby" Wade Walker, and also features a large ensemble cast that includes Amy Locane, Polly Bergen, Susan Tyrrell, Iggy Pop, Ricki Lake and Traci Lords, with appearances by Troy Donahue, Mink Stole, Joe Dallesandro, Joey Heatherton, David Nelson, Willem Dafoe, and Patricia Hearst.

The film centers on a group of delinquent youth who refer to themselves as "drapes" and their interaction with the rest of the town and its other subculture, the "squares", in 1950s Baltimore, Maryland. "Cry-Baby" Walker, a drape, and Allison, a square, disturb Baltimore society by breaking the subculture taboos and falling in love. The film shows what the young couple has to overcome to be together and how their actions affect the rest of the town.

Part of the film takes place at the now-closed Enchanted Forest amusement park in Ellicott City, Maryland. Others take place in the historic neighborhoods and towns of Hampden, Baltimore City, Reisterstown, Jessup, Milford Mill, and Sykesville, Maryland. The only scenes not filmed in Maryland were shot at Golden Oak Ranch in Santa Clarita Valley, California.

A box office failure during its initial release, the film has subsequently become a cult classic and spawned a Broadway musical of the same name which was nominated for four Tony Awards.